Everything about ceesdekker.net
Everything about ceesdekker.net
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Nanotechnology offers A variety of chances to add to biology. Here I will current illustrations where by nanofabrication – the ability to make confined constructions with dimensions at will – is employed to examine the biophysics of one molecules and cells. I will current some illustrations from our lab:
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Nanofabrication of electrodes with sub-5 nm spacing for transportation experiments on solitary molecules and steel clusters
2010, made a new way (‘wedging transfer’) to manipulate nanostructures; very first report of DNA translocation by graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into reliable-condition nanopores
Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en achieved 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
Several connected developments followed, in which our group established different transistor variants for instance solitary-electron transistors at area temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled various transistors into small proof-of-principle Digital circuits.
Instance (one) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in grey, the rim on the pore is highlighted in red, and also a 3D rendering from the movement of the https://www.ceesdekker.net DNA rod is shown.
The rotors harness Strength from a nanoscale h2o and ion circulation that's created by a static chemical or electrochemical probable gradient inside the nanopore, that are founded by way of a salt gradient or applied voltage, respectively. These synthetic nanoengines self-organize and work autonomously in physiological problems, suggesting methods to developing Strength-transducing motors at nanoscale interfaces.
It was in the course of this period that Dekker completed investigation on magnetic spin devices and on sounds in superconductors and semiconductors.
An built-in microfluidic System for quantifying drug permeation throughout biomimetic vesicle membranes
1999, very first measurement of your wavefunction of solitary molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive proof for any new Luttinger description of interacting electrons in nanotubes
2005, discovery in the system of DNA uncoiling by topoisomerase enzymes; discovery of lengthy-array conformational modifications in Mre11/DNA repair service complexes; and initial pressure measurements on a DNA molecule within a nanopore
Finally, I will briefly sketch a few of our Tips to check out the constructing of artificial cells, exclusively our initially ways to determine artificial mobile division.